세부내용
학력
2010
Ph.D. in Biochemistry, University of Maryland, Baltimore School of Pharmacy, Department of Pharmaceutical Sciences
2002
M.S. in Medicinal Chemistry, Chonbuk National University
2000
B.S. in Chemistry, Chonbuk National University
주요 경력
2010 - 2013
Postdoctoral Researcher, Massachusetts Institute of Technology
2004 - 2005
Researcher, POSTECH Biotech Center
2002 - 2004
Researcher, HS-Engelhard Research Center
수상
연구분야
대표논문
1. Lu, T.–T., Lee, S. J., Apfel, U. P., Lippard, S. J. “Aging-associated enzyme human clock-1: Substrate-mediated reduction of the diiron center for 5-demethoxyubiquinone hydroxylation”, Biochemistry,2013,52,2236-2244
2. Lee, S. J., McCormick, M., Lippard, S. J., Cho, U. S. “Control of substrate access to the active site in methane monooxygenase”,Nature,2013, 494,380-384
3. Michalek, J., Lee, S. J., Michel, S.L.J. “Cadmium coordination to the zinc binding domains of the non-classical zinc finger protein Tristetraprolin affects RNA binding selectivity”,JournalofInorganicBiochemistry,2012,112,32-38
4. Lee, S. J., Michalek, J., Besold, A., Rokita, S.E., Michel, S.L.J. “Classical Cys2His2zincfingerpeptidesarerapidlyoxidizedbyeitherH2O2orO2irrespectiveofmetalcoordination“,InorganicChemistry,2011,50,5442-5450
5. Besold, A., Lee, S. J., Lue Sue, N, Michel, S.L.J., Cymet, H.J. “Functional characterization of iron-substituted neural zinc finger factor 1: metal and DNA binding affinities”, JournalofBiologicalInorganicChemistry,2010,15,583-590
6. Lee, S. J. and Michel, S. L. J. “Cysteine oxidation enhanced by iron in tristetraprolin, a zinc finger protein”, InorganicChemistry,2010,49,1211-1219
주요 논문
주요 발표
특허